| CASE REPORT |
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| Year : 2018 | Volume
: 17
| Issue : 2 | Page : 93-97 |
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A case of hip disarticulation following parenteral narcotic abuse and literature reviews
Michael Ebiyon Ugbeye1, Kehinde Adesola Alatishe1, Olayinka Olawoye2
1 Department of Orthopaedic and Trauma Surgery, National Orthopaedic Hospital, Igbobi, Nigeria
2 Department of Surgery, Eko Hospitals Limited, Lagos, Nigeria
Correspondence Address:
Dr. Michael Ebiyon Ugbeye
Department of Orthopaedics and Trauma, National Orthopaedic Hospital, 120/124 Ikorodu Road, Igbobi, Lagos
Nigeria
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/njot.njot_27_18
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Pentazocine is one of the commonly prescribed narcotic analgesics for acute pain management such as post-operative or post-traumatic pain in developing countries. It has a high potential for abuse due to its euphoric effect. This abuse can lead to cutaneous, vascular, respiratory and central nervous system complications. Vascular complications include pseudoaneurysm formation, deep venous thrombosis, arteriovenous fistula, infected thrombi, arterial embolisation, infective endocarditis and gangrene. However, reports of amputation surgery for vascular complications following pentazocine abuse are few in the literature. We report a case of lower limb gangrene following a chronic abuse of self-administered injection pentazocine in a 38-year-old female who inadvertently ruptured her right femoral artery pseudoaneurysm. She had ligation of the bleeding vessel and an iliofemoral bypass surgery with synthetic polytetrafluoroethylene graft. This salvage procedure failed due to graft thrombosis, and she eventually had a right hip disarticulation.
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